Silencing of MicroRNA-21 Confers Radio-Sensitivity through Inhibition of the PI3K/AKT Pathway and Enhancing Autophagy in Malignant Glioma Cell Lines

Radiation is a core part of therapy for malignant glioma and is often provided following debulking surgery. However, resistance to radiation occurs in most patients, and the underlying molecular mechanisms of radio-resistance are not fully understood. Here, we demonstrated that microRNA 21 (miR-21),...

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Detalles Bibliográficos
Autores principales: Gwak, Ho-Shin, Kim, Tae Hoon, Jo, Guk Heui, Kim, Youn-Jae, Kwak, Hee-Jin, Kim, Jong Heon, Yin, Jinlong, Yoo, Heon, Lee, Seung Hoon, Park, Jong Bae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471817/
https://www.ncbi.nlm.nih.gov/pubmed/23077620
http://dx.doi.org/10.1371/journal.pone.0047449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471817/
https://www.ncbi.nlm.nih.gov/pubmed/23077620
http://dx.doi.org/10.1371/journal.pone.0047449

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