Parvin Overexpression Uncovers Tissue-Specific Genetic Pathways and Disrupts F-Actin to Induce Apoptosis in the Developing Epithelia in Drosophila

Parvin is a putative F-actin binding protein important for integrin-mediated cell adhesion. Here we used overexpression of Drosophila Parvin to uncover its functions in different tissues in vivo. Parvin overexpression caused major defects reminiscent of metastatic cancer cells in developing epitheli...

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Detalles Bibliográficos
Autores principales: Chountala, Maria, Vakaloglou, Katerina M., Zervas, Christos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471835/
https://www.ncbi.nlm.nih.gov/pubmed/23077599
http://dx.doi.org/10.1371/journal.pone.0047355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471835/
https://www.ncbi.nlm.nih.gov/pubmed/23077599
http://dx.doi.org/10.1371/journal.pone.0047355

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