Integration of SNP and mRNA Arrays with MicroRNA Profiling Reveals That MiR-370 Is Upregulated and Targets NF1 in Acute Myeloid Leukemia

BACKGROUND: Deregulated miRNA expression plays a crucial role in carcinogenesis. Recent studies show different mechanisms leading to miRNA deregulation in cancer; however, alterations affecting miRNAs by DNA copy number variations (CNV) remain poorly studied. RESULTS: Our integrative analysis includ...

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Detalles Bibliográficos
Autores principales: García-Ortí, Laura, Cristóbal, Ion, Cirauqui, Cristina, Guruceaga, Elisabet, Marcotegui, Nerea, Calasanz, María J., Castello-Cros, Remedios, Odero, María D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471844/
https://www.ncbi.nlm.nih.gov/pubmed/23077663
http://dx.doi.org/10.1371/journal.pone.0047717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471844/
https://www.ncbi.nlm.nih.gov/pubmed/23077663
http://dx.doi.org/10.1371/journal.pone.0047717

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