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Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients

BACKGROUND: The CYP2E1 and GSTM1 genes encode metabolic enzymes that have key functions in drug modification and elimination. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the possible effects of CYP2E1 and GSTM1 polymorphisms in 71 leprosy patients and in 110 individuals from the general populati...

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Detalles Bibliográficos
Autores principales: Pinto, Pablo, Salgado, Claudio Guedes, Santos, Ney, Alencar, Dayse O., Santos, Sidney, Hutz, Mara H., Ribeiro-dos-Santos, Ândrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471857/
https://www.ncbi.nlm.nih.gov/pubmed/23077626
http://dx.doi.org/10.1371/journal.pone.0047498