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Structural Mechanism of N-Methyl-D-Aspartate Receptor Type 1 Partial Agonism

N-methyl-D-aspartate (NMDA) receptors belong to a family of ionotropic glutamate receptors that contribute to the signal transmission in the central nervous system. NMDA receptors are heterotetramers that usually consist of two GluN1 and GluN2 monomers. The extracellular ligand-binding domain (LBD)...

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Detalles Bibliográficos
Autores principales: Ylilauri, Mikko, Pentikäinen, Olli T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471861/
https://www.ncbi.nlm.nih.gov/pubmed/23077649
http://dx.doi.org/10.1371/journal.pone.0047604