Soluble IL-2Rα (sCD25) Exacerbates Autoimmunity and Enhances the Development of Th17 Responses in Mice

A strong association exists between mutations at the IL2 receptor alpha chain (CD25) gene locus and susceptibility to a number of T cell driven autoimmune diseases. Interestingly, the presence of certain CD25 susceptibility alleles has been correlated with significantly increased levels of the solub...

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Detalles Bibliográficos
Autores principales: Russell, Shane E., Moore, Anne C., Fallon, Padraic G., Walsh, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471880/
https://www.ncbi.nlm.nih.gov/pubmed/23077668
http://dx.doi.org/10.1371/journal.pone.0047748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471880/
https://www.ncbi.nlm.nih.gov/pubmed/23077668
http://dx.doi.org/10.1371/journal.pone.0047748

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