Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

BACKGROUND: Hyperactivation of the mTORC2 signaling pathway has been shown to contribute to the oncogenic properties of gliomas. Moreover, overexpression of the mTORC2 regulatory subunit Rictor has been associated with increased proliferation and invasive character of these tumor cells. METHODOLOGY/...

Descripción completa

Detalles Bibliográficos
Autores principales: Bashir, Tariq, Cloninger, Cheri, Artinian, Nicholas, Anderson, Lauren, Bernath, Andrew, Holmes, Brent, Benavides-Serrato, Angelica, Sabha, Nesrin, Nishimura, Robert N., Guha, Abhijit, Gera, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471885/
https://www.ncbi.nlm.nih.gov/pubmed/23077666
http://dx.doi.org/10.1371/journal.pone.0047741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471885/
https://www.ncbi.nlm.nih.gov/pubmed/23077666
http://dx.doi.org/10.1371/journal.pone.0047741

Ejemplares similares