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Method for Evaluating Multiple Mediators: Mediating Effects of Smoking and COPD on the Association between the CHRNA5-A3 Variant and Lung Cancer Risk

A mediation model explores the direct and indirect effects between an independent variable and a dependent variable by including other variables (or mediators). Mediation analysis has recently been used to dissect the direct and indirect effects of genetic variants on complex diseases using case-con...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Spitz, Margaret R., Amos, Christopher I., Wu, Xifeng, Wetter, David W., Cinciripini, Paul M., Shete, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471886/
https://www.ncbi.nlm.nih.gov/pubmed/23077662
http://dx.doi.org/10.1371/journal.pone.0047705