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Method for Evaluating Multiple Mediators: Mediating Effects of Smoking and COPD on the Association between the CHRNA5-A3 Variant and Lung Cancer Risk
A mediation model explores the direct and indirect effects between an independent variable and a dependent variable by including other variables (or mediators). Mediation analysis has recently been used to dissect the direct and indirect effects of genetic variants on complex diseases using case-con...
Autores principales: | Wang, Jian, Spitz, Margaret R., Amos, Christopher I., Wu, Xifeng, Wetter, David W., Cinciripini, Paul M., Shete, Sanjay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471886/ https://www.ncbi.nlm.nih.gov/pubmed/23077662 http://dx.doi.org/10.1371/journal.pone.0047705 |
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