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Analysis of the Interferon Gamma (rs2430561, +874T/A) Functional Gene Variant in Relation to the Presence of Cardiovascular Events in Rheumatoid Arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular (CV) morbidity and mortality. Since interferon-gamma (IFN-γ) has a direct effect on inflammation, in this study we assessed the potential association of the IFNG functional gene variant rs...

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Detalles Bibliográficos
Autores principales: García-Bermúdez, Mercedes, López-Mejías, Raquel, González-Juanatey, Carlos, Corrales, Alfonso, Robledo, Gema, Castañeda, Santos, Miranda-Filloy, José A., Blanco, Ricardo, Fernández-Gutiérrez, Benjamín, Balsa, Alejandro, González-Alvaro, Isidoro, Gómez-Vaquero, Carmen, Llorca, Javier, Martín, Javier, González-Gay, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471910/
https://www.ncbi.nlm.nih.gov/pubmed/23077565
http://dx.doi.org/10.1371/journal.pone.0047166