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Donor Bone Marrow-Derived T Cells Inhibit GVHD Induced by Donor Lymphocyte Infusion in Established Mixed Allogeneic Hematopoietic Chimeras

Delayed administration of donor lymphocyte infusion (DLI) to established mixed chimeras has been shown to achieve anti-tumor responses without graft-vs.-host disease (GVHD). Herein we show that de novo donor BM-derived T cells that are tolerant of the recipients are important in preventing GVHD in m...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Yang, Yanping, Wang, Guanjun, Wang, Shumei, Yeap, Beow Yong, Sykes, Megan, Yang, Yong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471915/
https://www.ncbi.nlm.nih.gov/pubmed/23077554
http://dx.doi.org/10.1371/journal.pone.0047120