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Genetic Differences in Transcript Responses to Low-Dose Ionizing Radiation Identify Tissue Functions Associated with Breast Cancer Susceptibility

High dose ionizing radiation (IR) is a well-known risk factor for breast cancer but the health effects after low-dose (LD, <10 cGy) exposures remain highly uncertain. We explored a systems approach that compared LD-induced chromosome damage and transcriptional responses in strains of mice with ge...

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Detalles Bibliográficos
Autores principales: Snijders, Antoine M., Marchetti, Francesco, Bhatnagar, Sandhya, Duru, Nadire, Han, Ju, Hu, Zhi, Mao, Jian-Hua, Gray, Joe W., Wyrobek, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471924/
https://www.ncbi.nlm.nih.gov/pubmed/23077491
http://dx.doi.org/10.1371/journal.pone.0045394