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PROTS-RF: A Robust Model for Predicting Mutation-Induced Protein Stability Changes
The ability to improve protein thermostability via protein engineering is of great scientific interest and also has significant practical value. In this report we present PROTS-RF, a robust model based on the Random Forest algorithm capable of predicting thermostability changes induced by not only s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471942/ https://www.ncbi.nlm.nih.gov/pubmed/23077576 http://dx.doi.org/10.1371/journal.pone.0047247 |