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PROTS-RF: A Robust Model for Predicting Mutation-Induced Protein Stability Changes

The ability to improve protein thermostability via protein engineering is of great scientific interest and also has significant practical value. In this report we present PROTS-RF, a robust model based on the Random Forest algorithm capable of predicting thermostability changes induced by not only s...

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Detalles Bibliográficos
Autores principales: Li, Yunqi, Fang, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471942/
https://www.ncbi.nlm.nih.gov/pubmed/23077576
http://dx.doi.org/10.1371/journal.pone.0047247