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Glucose Decouples Intracellular Ca(2+) Activity from Glucagon Secretion in Mouse Pancreatic Islet Alpha-Cells
The mechanisms of glucagon secretion and its suppression by glucose are presently unknown. This study investigates the relationship between intracellular calcium levels ([Ca(2+)](i)) and hormone secretion under low and high glucose conditions. We examined the effects of modulating ion channel activi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471958/ https://www.ncbi.nlm.nih.gov/pubmed/23077547 http://dx.doi.org/10.1371/journal.pone.0047084 |