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Platelet-Derived Growth Factor CC-Mediated Neuroprotection against HIV Tat Involves TRPC-Mediated Inactivation of GSK 3beta

Platelet-derived growth factor-CC (PDGF-CC) is the third member of the PDGF family, and has been implicated both in embryogenesis and development of the CNS. The biological function of this isoform however, remains largely unexplored in the context of HIV-associated dementia (HAD). In the present st...

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Detalles Bibliográficos
Autores principales: Peng, Fuwang, Yao, Honghong, Akturk, Halis Kaan, Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471979/
https://www.ncbi.nlm.nih.gov/pubmed/23077641
http://dx.doi.org/10.1371/journal.pone.0047572