The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H–deficient mice

Chronic serum sickness leads to the formation of glomerular immune complexes; however, C57BL/6 mice do not develop glomerulonephritis unless complement factor H (CFH) is absent from the plasma. Here we studied the role for C5a receptor (R) in this setting. The exaggerated humoral immune response in...

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Detalles Bibliográficos
Autores principales: Alexander, Jessy J, Chaves, Lee, Chang, Anthony, Quigg, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472160/
https://www.ncbi.nlm.nih.gov/pubmed/22832515
http://dx.doi.org/10.1038/ki.2012.249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472160/
https://www.ncbi.nlm.nih.gov/pubmed/22832515
http://dx.doi.org/10.1038/ki.2012.249

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