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The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H–deficient mice

Chronic serum sickness leads to the formation of glomerular immune complexes; however, C57BL/6 mice do not develop glomerulonephritis unless complement factor H (CFH) is absent from the plasma. Here we studied the role for C5a receptor (R) in this setting. The exaggerated humoral immune response in...

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Detalles Bibliográficos
Autores principales:	Alexander, Jessy J, Chaves, Lee, Chang, Anthony, Quigg, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472160/ https://www.ncbi.nlm.nih.gov/pubmed/22832515 http://dx.doi.org/10.1038/ki.2012.249

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