Autophagy-receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

Autophagy targets pathogens, damaged organelles and protein aggregates for lysosomal degradation. These ubiquitinated cargoes are recognised by specific autophagy receptors, which recruit LC3-positive membranes to form autophagosomes. Subsequently, autophagosomes fuse with endosomes and lysosomes, t...

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Detalles Bibliográficos
Autores principales: Tumbarello, David A., Waxse, Bennett J., Arden, Susan D., Bright, Nicholas A., Kendrick-Jones, John, Buss, Folma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472162/
https://www.ncbi.nlm.nih.gov/pubmed/23023224
http://dx.doi.org/10.1038/ncb2589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472162/
https://www.ncbi.nlm.nih.gov/pubmed/23023224
http://dx.doi.org/10.1038/ncb2589

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