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Implications of fidelity difference between the leading and the lagging strand of DNA for the acceleration of evolution
Without exceptions, genomic DNA of living organisms is replicated using the leading and the lagging strand. In a conventional idea of mutagenesis accompanying DNA replication, mutations are thought to be introduced stochastically and evenly into the two daughter DNAs. Here, however, we hypothesized...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472163/ https://www.ncbi.nlm.nih.gov/pubmed/23087905 http://dx.doi.org/10.3389/fonc.2012.00144 |