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Ethyl pyruvate attenuates formalin-induced inflammatory nociception by inhibiting neuronal ERK phosphorylation

BACKGROUND: Ethyl pyruvate (EP) possesses anti-inflammatory activity. However, the potential anti-nociceptive value of EP for the treatment of the inflammatory nociception is largely unknown. We investigated whether EP could have any anti-nociceptive effect on inflammatory pain, after systemic admin...

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Detalles Bibliográficos
Autores principales: Lee, Min Jung, Jang, Minhee, Jung, Hyuk-Sang, Kim, Sung-Hoon, Cho, Ik-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472237/
https://www.ncbi.nlm.nih.gov/pubmed/22640699
http://dx.doi.org/10.1186/1744-8069-8-40