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In vivo USPIO magnetic resonance imaging shows that minocycline mitigates macrophage recruitment to a peripheral nerve injury

BACKGROUND: Minocycline has proven anti-nociceptive effects, but the mechanism by which minocycline delays the development of allodynia and hyperalgesia after peripheral nerve injury remains unclear. Inflammatory cells, in particular macrophages, are critical components of the response to nerve inju...

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Detalles Bibliográficos
Autores principales: Ghanouni, Pejman, Behera, Deepak, Xie, Jin, Chen, Xiaoyuan, Moseley, Michael, Biswal, Sandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472277/
https://www.ncbi.nlm.nih.gov/pubmed/22742763
http://dx.doi.org/10.1186/1744-8069-8-49