Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data

BACKGROUND: The detection of genomic copy number alterations (CNA) in cancer based on SNP arrays requires methods that take into account tumour specific factors such as normal cell contamination and tumour heterogeneity. A number of tools have been recently developed but their performance needs yet...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosén-Ansorena, David, Aransay, Ana María, Rodríguez-Ezpeleta, Naiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472297/
https://www.ncbi.nlm.nih.gov/pubmed/22870940
http://dx.doi.org/10.1186/1471-2105-13-192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472297/
https://www.ncbi.nlm.nih.gov/pubmed/22870940
http://dx.doi.org/10.1186/1471-2105-13-192

Ejemplares similares