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Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data
BACKGROUND: The detection of genomic copy number alterations (CNA) in cancer based on SNP arrays requires methods that take into account tumour specific factors such as normal cell contamination and tumour heterogeneity. A number of tools have been recently developed but their performance needs yet...
Autores principales: | Mosén-Ansorena, David, Aransay, Ana María, Rodríguez-Ezpeleta, Naiara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472297/ https://www.ncbi.nlm.nih.gov/pubmed/22870940 http://dx.doi.org/10.1186/1471-2105-13-192 |
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