Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most abundant type of genetic variation in eukaryotic genomes and have recently become the marker of choice in a wide variety of ecological and evolutionary studies. The advent of next-generation sequencing (NGS) technologies has made it pos...

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Detalles Bibliográficos
Autores principales: Dou, Jinzhuang, Zhao, Xiqiang, Fu, Xiaoteng, Jiao, Wenqian, Wang, Nannan, Zhang, Lingling, Hu, Xiaoli, Wang, Shi, Bao, Zhenmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472322/
https://www.ncbi.nlm.nih.gov/pubmed/22682067
http://dx.doi.org/10.1186/1745-6150-7-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472322/
https://www.ncbi.nlm.nih.gov/pubmed/22682067
http://dx.doi.org/10.1186/1745-6150-7-17

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