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Abrogating endocrine resistance by targeting ERα and PI3K in breast cancer

Antiestrogen therapies targeting estrogen receptor α (ER) signaling are a mainstay for patients with ER+ breast cancer. While many cancers exhibit resistance to antiestrogen therapies, a large body of clinical and experimental evidence indicates that hyperactivation of the phosphatidylinositol 3-kin...

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Detalles Bibliográficos
Autores principales: Fox, Emily M., Arteaga, Carlos L., Miller, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472546/
https://www.ncbi.nlm.nih.gov/pubmed/23087906
http://dx.doi.org/10.3389/fonc.2012.00145