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Gene location and DNA density determine transcription factor distributions in Escherichia coli
The diffusion coefficient of the transcription factor LacI within living Escherichia coli has been measured directly by in vivo tracking to be D=0.4 μm(2)/s. At this rate, simple models of diffusion lead to the expectation that LacI and other proteins will rapidly homogenize throughout the cell. Her...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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European Molecular Biology Organization
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472691/ https://www.ncbi.nlm.nih.gov/pubmed/22968444 http://dx.doi.org/10.1038/msb.2012.42 |