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Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain

Morphogens provide positional information for spatial patterns of gene expression during development. However, stochastic effects such as local fluctuations in morphogen concentration and noise in signal transduction make it difficult for cells to respond to their positions accurately enough to gene...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Radtke, Kelly, Zheng, Likun, Cai, Anna Q, Schilling, Thomas F, Nie, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472692/
https://www.ncbi.nlm.nih.gov/pubmed/23010996
http://dx.doi.org/10.1038/msb.2012.45