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Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain
Morphogens provide positional information for spatial patterns of gene expression during development. However, stochastic effects such as local fluctuations in morphogen concentration and noise in signal transduction make it difficult for cells to respond to their positions accurately enough to gene...
Autores principales: | Zhang, Lei, Radtke, Kelly, Zheng, Likun, Cai, Anna Q, Schilling, Thomas F, Nie, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472692/ https://www.ncbi.nlm.nih.gov/pubmed/23010996 http://dx.doi.org/10.1038/msb.2012.45 |
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