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A Combination of 3D-QSAR, Molecular Docking and Molecular Dynamics Simulation Studies of Benzimidazole-Quinolinone Derivatives as iNOS Inhibitors

Inducible Nitric Oxide Synthase (iNOS) has been involved in a variety of diseases, and thus it is interesting to discover and optimize new iNOS inhibitors. In previous studies, a series of benzimidazole-quinolinone derivatives with high inhibitory activity against human iNOS were discovered. In this...

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Detalles Bibliográficos
Autores principales:	Zhang, Hao, Zan, Jinhang, Yu, Guangyun, Jiang, Ming, Liu, Peixun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472740/ https://www.ncbi.nlm.nih.gov/pubmed/23109848 http://dx.doi.org/10.3390/ijms130911210

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