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High Mitochondrial DNA Copy Number and Bioenergetic Function Are Associated with Tumor Invasion of Esophageal Squamous Cell Carcinoma Cell Lines

We previously reported a gradual increase of relative mitochondrial DNA (mtDNA) copy number during the progression of esophageal squamous cell carcinoma (ESCC). Because mitochondria are the intracellular organelles responsible for ATP production, we investigated the associations among mtDNA copy num...

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Detalles Bibliográficos
Autores principales: Lin, Chen-Sung, Lee, Hui-Ting, Lee, Shu-Yu, Shen, Yao-An, Wang, Liang-Shun, Chen, Yann-Jang, Wei, Yau-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472741/
https://www.ncbi.nlm.nih.gov/pubmed/23109849
http://dx.doi.org/10.3390/ijms130911228