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α-Tocopherol at Nanomolar Concentration Protects PC12 Cells from Hydrogen Peroxide-Induced Death and Modulates Protein Kinase Activities

The aim of this work was to compare protective and anti-apoptotic effects of α-tocopherol at nanomolar and micromolar concentrations against 0.2 mM H(2)O(2)-induced toxicity in the PC12 neuronal cell line and to reveal protein kinases that contribute to α-tocopherol protective action. The protection...

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Detalles Bibliográficos
Autores principales: Zakharova, Irina O., Sokolova, Tatyana V., Bayunova, Liubov V., Vlasova, Yulia A., Rychkova, Maria P., Avrova, Natalia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472762/
https://www.ncbi.nlm.nih.gov/pubmed/23109870
http://dx.doi.org/10.3390/ijms130911543