Cellular Delivery of Doxorubicin via pH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(β-L-Malic Acid)

Doxorubicin (DOX) is currently used in cancer chemotherapy to treat many tumors and shows improved delivery, reduced toxicity and higher treatment efficacy when being part of nanoscale delivery systems. However, a major drawback remains its toxicity to healthy tissue and the development of multi-dru...

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Detalles Bibliográficos
Autores principales: Patil, Rameshwar, Portilla-Arias, Jose, Ding, Hui, Konda, Bindu, Rekechenetskiy, Arthur, Inoue, Satoshi, Black, Keith L., Holler, Eggehard, Ljubimova, Julia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472769/
https://www.ncbi.nlm.nih.gov/pubmed/23109877
http://dx.doi.org/10.3390/ijms130911681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472769/
https://www.ncbi.nlm.nih.gov/pubmed/23109877
http://dx.doi.org/10.3390/ijms130911681

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