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Virotherapy of Canine Tumors with Oncolytic Vaccinia Virus GLV-1h109 Expressing an Anti-VEGF Single-Chain Antibody

Virotherapy using oncolytic vaccinia virus (VACV) strains is one promising new strategy for cancer therapy. We have previously reported that oncolytic vaccinia virus strains expressing an anti-VEGF (Vascular Endothelial Growth Factor) single-chain antibody (scAb) GLAF-1 exhibited significant therape...

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Detalles Bibliográficos
Autores principales: Patil, Sandeep S., Gentschev, Ivaylo, Adelfinger, Marion, Donat, Ulrike, Hess, Michael, Weibel, Stephanie, Nolte, Ingo, Frentzen, Alexa, Szalay, Aladar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473019/
https://www.ncbi.nlm.nih.gov/pubmed/23091626
http://dx.doi.org/10.1371/journal.pone.0047472