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Plasma-Derived Exosomal Survivin, a Plausible Biomarker for Early Detection of Prostate Cancer
BACKGROUND: Survivin is expressed in prostate cancer (PCa), and its downregulation sensitizes PCa cells to chemotherapeutic agents in vitro and in vivo. Small membrane-bound vesicles called exosomes, secreted from the endosomal membrane compartment, contain RNA and protein that they readily transpor...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473028/ https://www.ncbi.nlm.nih.gov/pubmed/23091600 http://dx.doi.org/10.1371/journal.pone.0046737 |