Integrating Chemical Footprinting Data into RNA Secondary Structure Prediction

Chemical and enzymatic footprinting experiments, such as shape (selective 2′-hydroxyl acylation analyzed by primer extension), yield important information about RNA secondary structure. Indeed, since the [Image: see text]-hydroxyl is reactive at flexible (loop) regions, but unreactive at base-paired...

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Detalles Bibliográficos
Autores principales: Zarringhalam, Kourosh, Meyer, Michelle M., Dotu, Ivan, Chuang, Jeffrey H., Clote, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473038/
https://www.ncbi.nlm.nih.gov/pubmed/23091593
http://dx.doi.org/10.1371/journal.pone.0045160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473038/
https://www.ncbi.nlm.nih.gov/pubmed/23091593
http://dx.doi.org/10.1371/journal.pone.0045160

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