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Accurate Simulation and Detection of Coevolution Signals in Multiple Sequence Alignments
BACKGROUND: While the conserved positions of a multiple sequence alignment (MSA) are clearly of interest, non-conserved positions can also be important because, for example, destabilizing effects at one position can be compensated by stabilizing effects at another position. Different methods have be...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473043/ https://www.ncbi.nlm.nih.gov/pubmed/23091608 http://dx.doi.org/10.1371/journal.pone.0047108 |