Accurate Simulation and Detection of Coevolution Signals in Multiple Sequence Alignments

BACKGROUND: While the conserved positions of a multiple sequence alignment (MSA) are clearly of interest, non-conserved positions can also be important because, for example, destabilizing effects at one position can be compensated by stabilizing effects at another position. Different methods have be...

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Detalles Bibliográficos
Autores principales: Ackerman, Sharon H., Tillier, Elisabeth R., Gatti, Domenico L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473043/
https://www.ncbi.nlm.nih.gov/pubmed/23091608
http://dx.doi.org/10.1371/journal.pone.0047108

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