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MicroRNA-155 Modulates Treg and Th17 Cells Differentiation and Th17 Cell Function by Targeting SOCS1

MicroRNA (miR)-155 is a critical player in both innate and adaptive immune responses. It can influence CD4(+) T cell lineage choice. To clarify the role of miR-155 in CD4(+) CD25(+) regulatory T (Treg)/T helper (Th)17 cell differentiation and function, as well as the mechanism involved, we performed...

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Detalles Bibliográficos
Autores principales: Yao, Rui, Ma, Yu-Lan, Liang, Wei, Li, Huan-Huan, Ma, Zhi-Jun, Yu, Xian, Liao, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473054/
https://www.ncbi.nlm.nih.gov/pubmed/23091595
http://dx.doi.org/10.1371/journal.pone.0046082