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The Ionic and Hydrophobic Interactions Are Required for the Auto Activation of Cysteine Proteases of Plasmodium falciparum

The Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3 are major hemoglobinases and potential antimalarial drug targets. Our previous studies demonstrated that these enzymes are equipped with specific domains for specific functions. Structural and functional analysis of falcipains...

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Detalles Bibliográficos
Autores principales:	Sundararaj, Srinivasan, Singh, Deepak, Saxena, Ajay K., Vashisht, Kapil, Sijwali, Puran S., Dixit, Rajnikant, Pandey, Kailash C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473063/ https://www.ncbi.nlm.nih.gov/pubmed/23077573 http://dx.doi.org/10.1371/journal.pone.0047227

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