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Altered Nucleotide-Microtubule Coupling and Increased Mechanical Output by a Kinesin Mutant
Kinesin motors hydrolyze ATP to produce force and do work in the cell – how the motors do this is not fully understood, but is thought to depend on the coupling of ATP hydrolysis to microtubule binding by the motor. Transmittal of conformational changes from the microtubule- to the nucleotide-bindin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473065/ https://www.ncbi.nlm.nih.gov/pubmed/23077560 http://dx.doi.org/10.1371/journal.pone.0047148 |