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Reliable Single Chip Genotyping with Semi-Parametric Log-Concave Mixtures
The common approach to SNP genotyping is to use (model-based) clustering per individual SNP, on a set of arrays. Genotyping all SNPs on a single array is much more attractive, in terms of flexibility, stability and applicability, when developing new chips. A new semi-parametric method, named SCALA,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473070/ https://www.ncbi.nlm.nih.gov/pubmed/23077503 http://dx.doi.org/10.1371/journal.pone.0046267 |