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Prognostic value of LINE-1 retrotransposon expression and its subcellular localization in breast cancer
Long interspersed nuclear element 1 (L1) belongs to a family of retrotransposons. Expression of the normally repressed L1 retrotransposons has been shown to induce genome instability by creating DNA double-stranded breaks and chromosomal rearrangements through the process of retrotransposition. At p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473189/ https://www.ncbi.nlm.nih.gov/pubmed/23053642 http://dx.doi.org/10.1007/s10549-012-2246-7 |