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Sustained Local Delivery of Structurally Diverse HIV-1 Microbicides Released from Sublimation Enthalpy Controlled Matrices

PURPOSE: Use of coital-dependent products to prevent HIV-1 transmission has resulted in mixed success. We hypothesize that incorporation of antiviral drug candidates into a novel controlled delivery system will prolong their activity, making their use coital independent, thus increasing their chance...

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Detalles Bibliográficos
Autores principales: Gunaseelan, Simi, Gallay, Philippe A., Bobardt, Michael D., Dezzutti, Charlene S., Esch, Timothy, Maskiewicz, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473190/
https://www.ncbi.nlm.nih.gov/pubmed/22736232
http://dx.doi.org/10.1007/s11095-012-0811-8