Cargando…

H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

BACKGROUND: Transcription regulation in pluripotent embryonic stem (ES) cells is a complex process that involves multitude of regulatory layers, one of which is post-translational modification of histones. Acetylation of specific lysine residues of histones plays a key role in regulating gene expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Karmodiya, Krishanpal, Krebs, Arnaud R, Oulad-Abdelghani, Mustapha, Kimura, Hiroshi, Tora, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473242/
https://www.ncbi.nlm.nih.gov/pubmed/22920947
http://dx.doi.org/10.1186/1471-2164-13-424