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Conformational co-dependence between Plasmodium berghei LCCL proteins promotes complex formation and stability

Malaria parasites express a conserved family of LCCL-lectin adhesive-like domain proteins (LAPs) that have essential functions in sporozoite transmission. In Plasmodium falciparum all six family members are expressed in gametocytes and form a multi-protein complex. Intriguingly, knockout of P. falci...

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Detalles Bibliográficos
Autores principales: Saeed, Sadia, Tremp, Annie Z., Dessens, Johannes T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473356/
https://www.ncbi.nlm.nih.gov/pubmed/22877575
http://dx.doi.org/10.1016/j.molbiopara.2012.07.007