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Esrrb Is a Direct Nanog Target Gene that Can Substitute for Nanog Function in Pluripotent Cells

Embryonic stem cell (ESC) self-renewal efficiency is determined by the level of Nanog expression. However, the mechanisms by which Nanog functions remain unclear, and in particular, direct Nanog target genes are uncharacterized. Here we investigate ESCs expressing different Nanog levels and Nanog(−/...

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Detalles Bibliográficos
Autores principales: Festuccia, Nicola, Osorno, Rodrigo, Halbritter, Florian, Karwacki-Neisius, Violetta, Navarro, Pablo, Colby, Douglas, Wong, Frederick, Yates, Adam, Tomlinson, Simon R., Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473361/
https://www.ncbi.nlm.nih.gov/pubmed/23040477
http://dx.doi.org/10.1016/j.stem.2012.08.002