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Diverse phosphorylation patterns of B cell receptor-associated signaling in naïve and memory human B cells revealed by phosphoflow, a powerful technique to study signaling at the single cell level

Following interaction with cognate antigens, B cells undergo cell activation, proliferation, and differentiation. Ligation of the B cell receptor (BCR) leads to the phosphorylation of BCR-associated signaling proteins within minutes of antigen binding, a process with profound consequences for the fa...

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Detalles Bibliográficos
Autores principales: Toapanta, Franklin R., Bernal, Paula J., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3473368/
https://www.ncbi.nlm.nih.gov/pubmed/23087912
http://dx.doi.org/10.3389/fcimb.2012.00128