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Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
Hypoxia inducible factor (HIF) is known as the master regulator of the cellular response to hypoxia and is of pivotal importance during development as well as in human disease, particularly in cancer. It is composed of a constitutively expressed β subunit (HIF-1β) and an oxygen-regulated α subunit (...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474226/ https://www.ncbi.nlm.nih.gov/pubmed/23091723 http://dx.doi.org/10.1155/2012/436981 |