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Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips

Hypoxia inducible factor (HIF) is known as the master regulator of the cellular response to hypoxia and is of pivotal importance during development as well as in human disease, particularly in cancer. It is composed of a constitutively expressed β subunit (HIF-1β) and an oxygen-regulated α subunit (...

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Detalles Bibliográficos
Autor principal: Hagen, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474226/
https://www.ncbi.nlm.nih.gov/pubmed/23091723
http://dx.doi.org/10.1155/2012/436981