Cargando…

Chromosomes without a 30-nm chromatin fiber

How is a long strand of genomic DNA packaged into a mitotic chromosome or nucleus? The nucleosome fiber (beads-on-a-string), in which DNA is wrapped around core histones, has long been assumed to be folded into a 30-nm chromatin fiber, and a further helically folded larger fiber. However, when froze...

Descripción completa

Detalles Bibliográficos
Autores principales: Joti, Yasumasa, Hikima, Takaaki, Nishino, Yoshinori, Kamada, Fukumi, Hihara, Saera, Takata, Hideaki, Ishikawa, Tetsuya, Maeshima, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474659/
https://www.ncbi.nlm.nih.gov/pubmed/22825571
http://dx.doi.org/10.4161/nucl.21222