Enzymatic Relay Mechanism Stimulates Cyclic GMP Synthesis in Rod Photoresponse: Biochemical and Physiological Study in Guanylyl Cyclase Activating Protein 1 Knockout Mice

Regulation of cGMP synthesis by retinal membrane guanylyl cyclase isozymes (RetGC1 and RetGC2) in rod and cone photoreceptors by calcium-sensitive guanylyl cyclase activating proteins (GCAP1 and GCAP2) is one of the key molecular mechanisms affecting the response to light and is involved in congenit...

Descripción completa

Detalles Bibliográficos
Autores principales: Makino, Clint L., Wen, Xiao-Hong, Olshevskaya, Elena V., Peshenko, Igor V., Savchenko, Andrey B., Dizhoor, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474714/
https://www.ncbi.nlm.nih.gov/pubmed/23082185
http://dx.doi.org/10.1371/journal.pone.0047637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474714/
https://www.ncbi.nlm.nih.gov/pubmed/23082185
http://dx.doi.org/10.1371/journal.pone.0047637

Ejemplares similares